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Navitoclax-piperazine (ABT-263-piperazine) is a B-cell lymphoma extra large (BCL-XL) inhibitor
BxPC-3 and Panc-1
InChiKey: GJMNAFGEUJBOCE-MEQIQULJSA-N
24)25)21(30)28-16-5-6-20(27-12-16)31-19-4-3-8-26-14(19)2
Formula: C41H42N10O6
Gap19 amine A-D3 Navitoclax-piperazine (ABT-263-piperazine) is a B-cellGap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40 pannexin 1 hemichannels. Gap19 has protective effects against myocardial. Product information CAS Number: 1507930 57 5 Molecular Weight: 1161. 44
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