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Aβ42-IN-1 Catalog No.:M16263-C inhibits inflammatory responses via MAPK

SKU: 11225924842

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Description

inhibits inflammatory responses via MAPK and NF-κB pathways in vitro and in vivo

It has been shown to scavenge DPPH radicals with an EC50 value of 0

2012 Aug 17

InChiKey: QMNWISYXSJWHRY-YLNUDOOFSA-N

InChiKey: RDUAJIJVNHKTQC-UJECXLDQSA-N

Aβ42-IN-1 Catalog No.:M16263-C inhibits inflammatory responses via MAPKA42 IN 1, compound 1v, is a novel, potent and orally active secretase modulator (GSM). A42 IN 1 potently reduced A42 levels with an IC50 value of 0. 091 M without CYP3A4 inhibition. A42 IN 1 shows a sustained pharmacokinetic profile. Product information Molecular Weight: 499. 00 Formula: C29H27ClN4O2 Chemical Name: 5 (8 ([1, 1' biphenyl] 4 ylmethoxy) 2 methylimidazo[1, 2 a]pyridin 3 yl) N ethylpicolinamide hydrochloride Smiles: Cl.

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