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Small molecule modulation of Smoothened activity
15(10):3368-72
Formula: C21H20ClF2N3O3
(2005) J Med Chem
Masitinib inhibits cell growth and PDGFR phosphorylation in two novel ISS cell lines
Liarozole Size:Contact [email protected] for quotation Small molecule modulation of SmoothenedLiarozole (R75251; R85246) is an imidazole derivative and orally active retinoic acid (RA) metabolism blocking agent (RAMBA). Liarozole inhibits the cytochrome P450 (CYP26) dependent 4 hydroxylation of retinoic acid (IC50=7 M), resulting in increased tissue levels of retinoic acid. Liarozole shows antitumoral properties. Product information CAS Number: 115575 11 6 Molecular Weight: 308. 76 Formula: C17H13ClN4 Chemical Name: 6 [(3 chlorophenyl)(1H