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A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer
CAS Number: 2070015-16-4
Clorsulon is antihelminthic compound that is a potent fasciolicide
CAS Number: 315704-66-6
ITF2357 (Givinostat) ate (Monocaprin) A small molecule modulates JumonjiGivinostat or gavinostat, aslo known as ITF2357, is a potent and orally active histone deacetylase inhibitor with potential anti inflammatory, anti angiogenic, and antineoplastic activities. It is a hydroxamate used in the form of its hydrochloride. Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis. ITF2357 reduces cytokines and protects islet cells in vivo and