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Nirogacestat dihydrobromide - CAS# 1962925-29-6 ant metabolite N-desmethyl Netupitant reducing tumor burden and extends

SKU: 29292138736

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Description

reducing tumor burden and extends survival in lymphoma pdx models

Belanova M

Formula: C21H24O10

79 µM respectively

Formula: C10H12N5O5PS

Nirogacestat dihydrobromide - CAS# 1962925-29-6 ant metabolite N-desmethyl Netupitant reducing tumor burden and extendsNirogacestat dihydrobromide (PF 3084014 dihydrobromide) is a reversible, orally bioavailable, noncompetitive, and selective secretase inhibitor with an IC50 of 6. 2 nM. Inhibition of Notch signaling by Nirogacestat dihydrobromide while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor dependent cancers. Product information CAS Number: 1962925 29 6 Molecular Weight: 651. 47 Formula: C27H43Br2F2N5O

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